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KMID : 0355220120370010027
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Journal of Korean Academy Oral Medicine
2012 Volume.37 No. 1 p.27 ~ p.33
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The Effects of Corticosteroid Solutions in OLP Patients
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Jeong Su-Min
Park Su-Hyeon
Ok Soo-Min
Heo Jun-Young
Ko Myung-Yun
Ahn Yong-Woo
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Abstract
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Oral lichen planus(OLP) is a chronic inflammatory disease with cell-mediated immune responses, but the exact cause is unknown. The treatment aim of OLP is not complete cure but to alleviate symptoms. In this study, two kinds of corticosteroid gargling solutions used for comparing the effects. From 2002 to 2010, 180 patients diagnosed with oral lichen planus and received topical steroid therapy in the Pusan National University Dental Hospital. Each of two types of solution contained dexamethasone (dexamethasone disodium phosphate) and prednisolone (solondo®). A period of relief of symptoms and recurrence was recorded. The group using solution containing dexamethasone(dexa gargle) was prescribed to 33 patients(25 female, 8 male) and another group containing prednisolone (solon gargle) included 147 patients (114 female, 33 male). The effect of dexa gargle seemed faster than the solon gargle. There was no significant difference for recurrent rate between the groups using dexa and solon gargle.
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KEYWORD
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Corticosteroid gargle, Dexamethasone gargle, Oral lichen planus, Prednisolone gargle, Topical steroid
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